Medical Device Regulatory Requirements in Luxembourg

Governed by the European Union Medical Device and IVD Regulations (EU 2017/745, 2017/746)

Regulatory Authority Ministry of Health
Regulatory Authority Website Link Click Here
Device Classification I, IIa, IIb and III
Medical Device Regulations Medical Devices Regulation | Click Here
IVD Classification A,B,C,D
In Vitro Diagnostics Regulations Regulation (EU) 2017/746 (IVDR) on in vitro diagnostic medical devices | Click Here
Device Classification Guidelines MDCG 2021-24 Guidance on classification of medical devices | Click Here
Registration Process Medical Devices Registration | Click Here
Registration Timeline For Class I, it is 1 to 2 months and for other classes, it depends on the notified body and type of product
Conformity Assessment Route

Chapter 5, section 2, Article 52 Annexes IX to XI

Technical Documentation Format

EU MDR 2017/745 Annex II, III

Requirement of Authorized Representative Yes
Language Requirement Labels must be in French or German or Luxembourgish LanguageLabels for AIMD should be in French or German
Labeling Requirements
For active implantable medical devices , the information to be provided to users and patients must be written in one of the following languages:  French or German .
 
For medical devices and in vitro diagnostic medical devices , the information to be provided to users and patients must be written in one of the following languages:  French, German or Luxembourgish .
 
For devices intended exclusively for professional use , the information may also be written in English.
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Clinical Trials Information

In Luxembourg , any request for clinical investigation or substantial modification of a clinical investigation is also subject to prior authorization from the Minister, based on the scientific and ethical opinions of the Health Directorate and the National Research Ethics Committee (Art. 27 of the Law of March 8, 2018 relating to hospital establishments and hospital planning ).

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Declaration of Conformity

Annex II, article 19 of EUMDR 2017/745

Certificate of Free Sale

The Certificate of Free Sale (CLV) is a document that certifies that a medical device from a Luxembourg manufacturer or representative complies with applicable legislation and may be marketed in the European Union (EU). The CLV is intended for a health authority in an importing country outside the EU. It is requested by a manufacturer or representative for the purpose of exporting a medical device (MD) or an in vitro diagnostic medical device (IVD) outside the EU.

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Field Safety Corrective Action

Regarding FSNs (Field Safety Notices), reflecting the linguistic situation of the medical sector in Luxembourg, we suggest at least the French and German versions in addition to the English version. FSCA notifications must also be accompanied by:

  • the list of Luxembourg users/customers concerned by this FSCA,
  • an overview of the number of relevant products supplied on the Luxembourg market,
  • a confirmation of transmission of the FSN to Luxembourg users/clients.
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Additional Information

Any medical device bearing the CE marking, indicating that it has been subject to a conformity assessment, can be made available on the market and put into service.

Contact Email meddevices@ms.etat.lu
Contact Website Click Here
Disclaimer: This website sources information from regulatory authorities and aims for accuracy, but regulations may change without notice. Users are advised to verify details with relevant authorities before making compliance decisions. We are not responsible for errors, omissions, or outdated content.

The above information is last updated on 07/Oct/2025

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